Many of you reported to my Office with a complaint be hypothyroidism only said by your provider of primary health care which is normal in the tests. Guess what? You are correct! But it is you. However, they have not gone far enough to document what knows that it is true. The thyroid gland most of the time is to produce adequate amounts of thyroid. However, once it leaves the gland, seizes brain and respond to environmental cues, sleep, stress, exercise, etc. This answer changes the activity of enzymes that control the conversion of the thyroid hormone on its most active form known as T3. This has to be assessed to determine adequately its activity of thyroid true. I have included a graph of comments below of this physiology.
The following is a review of the thyroid axis:
HYPOTHALAMUS-> SAR (thyrotropin releasing this hormone decreases in times of stress)-->pituitary ---------> TSH (thyroid stimulating hormone - also decreased in times of stress)-->thyroid (gland produces four types of thyroid hormone, T1-4 - 90% of the production as T4, 10% of the production as T3.) They are andT1 T2< 1%="" of="">
T3 is 5 times more potent than T4. As such, 50-80% of T4 is converted to his more powerful counterpart, T3. The conversion occurs through the activity of enzymes called DEIODINASES. They are known as D1-3 enzymes. This is how the brain controls the activity of thyroid and that is why in times of stress, reduces the activity of the thyroid.
D1 and D2 control conversion in muscles and nerves. When stress occurs, however, the enzyme is activated D3 convert T4--> rT3-reverseT3. Reverse T3 is not able to link the thyroid receptor and acts as a "thyroid brake" limit the metabolic effects of thyroid.
Primary stress hormone that controls this is CRH (corticotropin releasing hormone). This is also released by the hypothalamus in the brain. It stimulates the release of ACTH (Adrenocorticotropic hormone). Stimulates the adrenal gland to release adrenaline and cortisone, the primary stress hormones. When CRHis, SAR and TSH are reduced. Thinking in this way. The main function of the thyroid is to establish the metabolic rate and consumption of oxygen in the body. When reduces thyroid, fatigue, decreased body temperature, weight management problems, constipation, loss of hair, etc. may have. This occurs under stress because the brain thinks it should give priority to feeding the stress response that may involve the execution or struggling to escape from danger. Reduction of their metabolic rate by reducing the activity of the thyroid will help the body to maintain sufficient fuel for the response of stress/exhaust. When primary care providers evaluating thyroid, generally only measured TSH and T4 perhaps. Do not you look at the rest of the chemical.
Thus, when say you that the thyroid is normally, they are technically correct, but they are not responsible for the environmental influences that all endure these days. Not to mention, there are issues/micro-nutrients in our food supply that deny us adequate support of micronutrients that supports the normal conversion of the thyroid. Without evaluating the levels of T3 and rT3, there is no confirmation of environment / nutritional problems and the origin of the symptoms of hypothyroidism may be lost. But here is the key point! If your brain does not allow conversion to T3 and maneuvers to rT3 instead, it is doing as compensation for his lifestyle and stressors in an effort to protect your computer. In many cases, attempting to provide T3 to compensate for altered conversion you will not resolve the problem as the brain is seen as going against his programming. In my experience, most of the time, you can get some improvements to this chemistry. However, it cannot achieve complete rebalancing without a tribute to their stress. Sorry, this is just the reality of how it works. It is a very complex chemistry required a more comprehensive assessment to the symptoms of low activity. More and more doctors are beginning to look more thoroughly. Hopefully this first shall educate them a little bit about what you should be looking and asking your doctor coming in. You cannot get a favourable response to its query, unfortunately. Take heart, there are more of us out there who listen.
I hope this helps...
My name is Courtney Ridley, MD, FACOG. I'm a gynecologist obstetrician certified by the Board which also incorporates functional medicine in my practice. Functional medicine approaches are starting to make inroads into the general practice, but there is still work to be done. This is the reason for this and subsequent shipments. My website is: http://www.integrative-gynecology.com/
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